April 30, 2018April 20, 2018 by Inna Bakman-Sanchez

Latest Work by Zeglis’ Group

Zeglis‘ Lab at Hunter College is fighting colorectal cancer!

Using inverse electron demand Diels–Alder (IEDDA) reaction on ¹⁷⁷Lu-labeled Tz radioligand and an immunoconjugate of the huA33 antibody (huA33-TCO) they improved pretargeted radioimmunotherapy (PRIT).

Read: http://bit.ly/2JfoCzF

Left: Schematic of Pretargeted radioimmunotherapy (PRIT) based on the Inverse electron demand Diels–Ald (IEDDA) reaction. Right: Longitudinal therapy study.

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