Read the latest publication by Prof. Guillermo Gerona-Navarro (Brooklyn College) and collaborators, where they investigate the
molecular basis for Olinone’s selective recognition by two bromodomains (BrDs) proteins that play a critical role in numerous diseases including cancer.
Congrats to our PhD student Nana Agyemang of the Murelli lab (Brooklyn College, CUNY) on his first-author publication “Divergent Synthesis of a Thiolate-Based alpha-Hydroxytropolone Library with a Dynamic Bioactivity Profile” published in RSC Advances.
This manuscript describes Nana’s development of a new strategy to access substituted hydroxytropolones, and its use in identifying new molecules with sub-micromolar activity against three human pathogens – hepatitis B virus, herpes simplex virus-1, and Cryptococcus neoformans.
Biological studies were carried out in collaboration with the Tavis, Morrison, and Donlin labs at Saint Louis University School of Medicine.
Check out the manuscript here: https://pubs.rsc.org/en/content/articlehtml/2019/RA/C9RA06383H
Congrats to PhD Student Lauren Bejcek of the Murelli lab (Brooklyn College) on her first author research publication, “Maltol- and allomaltol-derived oxidopyrylium ylides: Methyl substitution pattern kinetically influences [5 + 3] dimerization versus [5 + 2] cycloaddition reactions”, recently accepted in Journal of Organic Chemistry.
This work was a collaborative effort across multiple CUNY research labs including co-corresponding author Prof. Edyta Greer (Baruch College), Prof. Alec Greer (Brooklyn College) and Prof. William Hersh (Queens College).
Other co-authors include former postdoctoral associate Aswin Garimalla and Brooklyn College undergraduate Duygu Suyabatmaz.
See the accepted manuscript here:
Prof. Guoqi Zhang Lab at John Jay College of Criminal Justice with collaborators report the FIRST examples of Vanadium-catalyzed esters and amides – a significant conceptual advance in the field of reductive transformations!
Read their paper in ACS Publications: