Latest Work by Zeglis’ Group

Zeglis‘ Lab at Hunter College is fighting colorectal cancer!
Using inverse electron demand Diels–Alder (IEDDA) reaction on 177Lu-labeled Tz radioligand and an immunoconjugate of the huA33 antibody (huA33-TCO) they improved pretargeted radioimmunotherapy (PRIT).
 
Left: Schematic of Pretargeted radioimmunotherapy (PRIT) based on the Inverse electron demand Diels–Ald (IEDDA) reaction. Right: Longitudinal therapy study. 

Latest Publication by Dr. Waqar Rizvi

Latest publication by recent PhD graduate Dr. Waqar Rizvi at Hunter College, is one step closer to better treatment for age-related macular degeneration, cancer, and various skin disorders using conjugates of saccharides to photosensitizers. In this study, they look into the photophysical properties, in vitro cell uptake, and photo-dynamic efficiency of the carbon-1 vs the carbon-3 conjugates.

Read: http://bit.ly/2uVbOMO

Review by Ulijn Group

A review by Ulijn Group presents a perspective on developments in the design of supramolecular materials with customizable properties.
The examples discussed are based on self-assembling peptide and saccharide-based amphiphiles – ideally suited to fundamental, systematic studies and also considered for applications in environmental remediation, food science, cosmetics, and nanomedicine.
Supramolecular energy landscapes dictate structure and function.